RT Saloni: Guys, how do you invent a vaccine? Or wilder, how do you invent a vaccine during your PhD?! In a new episode of Hard Drugs, we talked to so...

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  Scientists have developed a nasal spray treatment that reversed key signs of brain aging in animal studies. The spray delivers a molecule that restores cellular waste-clearing processes in the brain, improving cognitive function in older mice. Researchers hope to advance the treatment to human clinical trials.

• One-and-Done Heart Disease Prevention? Scientists Show It May Be Possible

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• We've promised to cure all disease for decades. Latest: $2.1B and a Nobel

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  Arc Institute has raised $2.1 billion and secured a Nobel Prize for its work on programmable biology and RNA medicine, aiming to move beyond incremental drug development toward a systematic "constellation" approach to curing previously untreatable diseases. The institute's model combines academic freedom with long-term funding to tackle fundamental biological challenges.

• Has pancreatic cancer met its match?

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  Pancreatic cancer is notoriously difficult to treat due to the dense, protective tissue surrounding tumors, but a new drug combination targeting a specific protein called KRAS may offer a breakthrough. Clinical trials show promising results in shrinking tumors and improving survival rates, potentially transforming the outlook for one of the deadliest cancers.

• Is “colorectal cancer” rising in “young people”?

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  Colorectal cancer rates are increasing among younger adults, but the article urges caution in interpreting the trend, noting that absolute risk remains low and that the rise is partly due to improved detection and screening practices.