Unexpected cancer mutations in brain's immune cells may help fuel Alzheimer's
研究发现大脑免疫细胞中的意外癌症突变可能促进阿尔茨海默病发展,这些在小胶质细胞中发现的突变通常与癌症相关,但在阿尔茨海默病患者大脑中异常活跃,可能加剧神经退行性病变。
研究发现大脑免疫细胞中的意外癌症突变可能促进阿尔茨海默病发展,这些在小胶质细胞中发现的突变通常与癌症相关,但在阿尔茨海默病患者大脑中异常活跃,可能加剧神经退行性病变。
The prevalence of dementia at given ages has decreased compared to decades ago. Today's 90-year-olds have less than half the dementia risk compared to those in 1984.
Research indicates that the heritability of human lifespan is approximately 50% when using a redefined concept of heritability. This suggests genetic factors account for about half of lifespan variation, while environmental and other factors contribute the remaining half.
Heritability measures how much of the variation in a trait within a population is due to genetic differences. It does not indicate how much of an individual's trait is determined by genes versus environment. The concept is often misunderstood in discussions about intelligence, personality, and other complex traits.