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SpudCell: Scientists Made a Cell with Most of the Hallmarks of Life

Scientists have created SpudCell, a synthetic cell that exhibits growth, division, and complex chemical reactions, built from a minimal set of genes. The breakthrough advances synthetic biology and could lead to new insights into life's fundamental principles.

Background

- Scientists have created "SpudCell," a synthetic cell that exhibits most of the hallmarks of life — it can grow, divide, and process genetic information — but it is not derived from a natural organism. It's a major step in synthetic biology. - The cell was built from the bottom up, using a genome designed and assembled in the lab, then inserted into a cellular chassis. This builds on decades of work in genomics and synthetic biology, notably J. Craig Venter's team creating the first synthetic bacterial cell in 2010. - "SpudCell" is not a new species of potato (the name is a lab nickname). It is a streamlined, minimal cell meant to help researchers understand the fundamental requirements for life. - Why it matters: If scientists can design and control a living cell from scratch, they could one day program cells to produce fuels, medicines, or materials, or to clean up pollution. It also raises questions about what "life" means and what ethical boundaries might apply.

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