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The prevalence of dementia at given ages has decreased compared to decades ago. Today's 90-year-olds have less than half the dementia risk compared to those in 1984.

An Israeli analyst cites accounts from guards at Sde Teiman detention site describing Palestinians being raped and sexually assaulted using dogs. Human rights organizations including B'Tselem and Euro-Mediterranean Human Rights Monitor have documented these cases.

Aaron Levie notes that AI architecture requires frequent dramatic upgrades due to rapid model progress, making previous work obsolete every few quarters. Systems built to compensate for model limitations become useless as context windows expand and compute solutions change. This constant obsolescence drives intense work in the AI field.

Jared Friedman told 2,000 future founders in Bengaluru that India is starting a second wave of world-class AI native products for global markets. He emphasized execution is everything and Indian engineering talent can beat US teams. The best founders build at the edge of technical possibilities using AI coding capabilities.

Congressman Thomas Massie reported that between midnight and 2am, attempts were made to pass two versions of FISA that would have allowed unconstitutional surveillance of Americans. Both versions were stopped, and lawmakers were given two more weeks to fix the legislation.

Startup School India received over 25,000 applications for 2,000 spots, setting a record for the highest number of applicants in the program's history across all locations worldwide.

Patrick Collison reports that using coding agents to analyze his genome revealed a 30x higher predisposition to melanoma, enabling targeted supplements and increased screening. He notes the analysis cost less than $100, with genome sequencing costing a few hundred dollars.

Norway has tested its first driverless bus in regular traffic without a safety driver. If successful, the autonomous buses will be available to passengers starting in May.

The AI revolution remains highly concentrated in the Bay Area, with 91% of global AI private market cap located within a one-hour radius. This concentration mirrors previous tech waves like semiconductors and the internet, despite startup activity spreading worldwide in recent decades.

The post highlights that railroad investment was historically unprecedented, noting that the accompanying graph uses a logarithmic scale to illustrate this point.

Six Y Combinator-backed Indian founders spoke at Startup School India. Their companies have a combined value exceeding $25 billion and have created over 250,000 jobs in India.

Y Combinator's Startup School will be launching in India tomorrow. The announcement was made by Jared Friedman and shared by Paul Graham.

A watchmaker tells a customer their watch cannot be repaired and suggests selling it at auction. The customer reveals they originally purchased the watch at an auction, to which the watchmaker responds that this is common with such watches.

Programming is particularly effective at teaching thinking skills because programs are built from ideas. This makes computer science valuable to study even in the AI era, as thinking well remains important.

Ron discovered how to be the investor of the future by accident, not by foreseeing startup investing trends or forcing himself to behave a certain way. It would feel unnatural for him to behave any other way.

Japanese dealers routinely include timegrapher measurements in their watch listings, while Northern European dealers provide them upon request. Italian dealers often appear unfamiliar with timegraphers altogether.

Brian Armstrong states that agentic commerce is not yet priced in and that machine-to-machine payments will increase demand for the digital dollar beyond current estimates. He suggests the agentic economy could be larger than the human economy, with Coinbase building infrastructure for both.

Channel 4 News reported on Israel targeting ambulances and paramedics in Lebanon, including a recent 'triple hit' where Israel attacked an ambulance, then paramedics who went to help, and then further paramedics also trying to assist.

A BBC documentary documents over 160 cases of children killed in Gaza, with 95 shot in the head and chest. The documentary's findings are presented as evidence of the conflict's impact on children.

Working just hard enough to get by leaves little margin for error, similar to doing things at the last minute.